New frontiers of molecular epidemiology of infectious diseases Edited by: Serge Morand, François Beaudeau, Jacques Cabaret 1st Edition., 2012, VIII, 340 p. 70 illus., 18 in color.   Contents: Preface. Introduction. Part 1  – Methods and tools in molecular epidemiolog.- 1 Molecular typing of bacterial pathogens: a tool for the epidemiological study and control of infectious diseases. Part 2 – Contribution of population genetic.- 2 Molecular epidemiology and evolutionary genetics of infectious diseases.-3 Population genetics and molecular epidemiology of infectious diseases. Part 3 – Contribution of population and evolutionary epidemiolog.- 4 Modelling the dynamics of host-parasite interactions: basic principles.-5 Evolution of virulence: intuitions and models. Part 4 –Case studie.- 6 Molecular epidemiology of tuberculosis.-7 Pneumocystis molecular phylogeny: a way to understand both pneumocystosis natural history and host taxonomy. 8 Hantavirus genetic diversity. Part 5  – New integrations.- 9 Nasal methicillin-resistant coagulase-negative Staphylocococci: a reservoir of mecA gene for Staphylococcus aureus.-10 Molecular knowledge of mechanisms of helminth resistance: importance for diagnostic and epidemiology.-11 Molecular epidemiology of disease resistance genes with perspectives for researches on biological invasions and hybrid zones.-12 How does biodiversity influence the ecology of infectious disease?-13 Epidemiological interaction at the wildlife/livestock/human interface: can we anticipate emerging infectious diseases in their hotspots? A framework for building emerging diseases processes in their hot spots. Conclusion. Index.   Key words : Infectious diseases, microbiology, molecular epidemiology, parasitology, population biology

• Blasdell K., Henttonen H., Buchy P., 2012. Hantavirus genetic diversity. In: Morand S., Beaudeau F. and Cabaret S., editors. New frontiers of molecular epidemiology of infectious diseases. Springer, 179-216.
• Caron S., Morand S., de Garine-Wichatitsky M., 2012. Epidemiological interaction at the wildlife/livestock/human interface: Can we anticipate emerging infectious diseases in their hotspots? A framework for building emerging diseases processes in their hot spots. In: Morand S., Beaudeau F. and Cabaret S., editors. New frontiers of molecular epidemiology of infectious diseases. Springer, 311-332.
• Chabé C., Hugot J.P., Dei-Cas E., 2012. Pneumocystis molecular phylogeny: a way to understand both pneumocystosis natural history and host. In: Morand S., Beaudeau F. and Cabaret S., editors. New frontiers of molecular epidemiology of infectious diseases. Springer, 149-178.
• Charbonnel N., Cosson J.F., 2012. Molecular epidemiology of disease resistance genes with perspectives for researches on biological invasions and hybrid zones. In: Morand S., Beaudeau F. and Cabaret S., editors. New frontiers of molecular epidemiology of infectious diseases. Springer, 255-290.
• Vourc’h G., Plantard O., Morand S. , 2012. How does biodiversity influence the ecology of infectious disease? In: Morand S., Beaudeau F. and Cabaret S., editors. New frontiers of molecular epidemiology of infectious diseases. Springer, 291-309.

Abstract:  South East Asia displays a high level of mammal endemism and the highest number of threatened and data deficient mammal species. However, the South East Asian biodiversity is still highly unexplored. Because of the runaway global changes, a better biological knowledge of this region is urgently required to improve the conservation and the management of its biodiversity.

The first aim of this chapter is to present recent published data on a biodiversity inventory of the Rattini murine rodents from this region based onmolecularmarkers (Pagès et al., 2009). In this first study, we applied themethod proposed by Pons et al. (2006) that determines with no a priori the locations of ancestral nodes that define putative species in order to investigate the current taxonomy of the Rattini tribe.

Our second aim concerns the intraspecific genetic structure of a rare and threatened South East Asian mammal species: the murine rodent Leopoldamys neilli , endemic to karst habitats . In this latter study, our results evidenced a high geographic structure of the genetic diversity of this species. The observed highly divergent genetic lineages would have to be considered as distinct evolutionary units or at least as Management units. These results are essential for the best conservation issues of species endemic to karsts and to South East Asia, in general.